An experimental small molecule helped restore the removal of mitochondria from dopamine-producing neurons in the brain. The findings may help in the development of new therapies for Parkinson’s disease.
A new hydrogel that acts as a gateway to transfer stem cells into the brain and facilitate repair to damaged tissue may effectively treat neurological conditions like Parkinson’s disease and stroke.
Farnesol, a naturally occurring compound found in berries and other fruits, prevents the loss of dopamine-producing neurons and reverses Parkinson’s associated damage to the brain in mouse models.
A new study reveals adults with ADHD have an increased risk of developing nervous system, respiratory, musculoskeletal, and metabolic diseases. ADHD was also associated with a slightly increased risk of Parkinson’s disease, dementia, and cardiovascular…
Sporadic Parkinson’s disease appears to be caused by a blockage in the pathway that helps regulate mitochondria.
Weekly musical dance classes can help to improve daily living and motor functions in those with mild-to-moderate Parkinson’s disease.
Chronic gut inflammation can trigger the clumping of alpha-synuclein in the walls of the colon, a new study reports. Researchers found chronic inflammation in the gut during early life can exacerbate the clumping of alpha-synuclein in the brains of old…
NfL, a single biomarker in the blood, can accurately predict the presence of underlying neurodegenerative disorders, such as FTD and ALS, in people with cognitive problems.
In Parkinson’s disease, alpha-synuclein binds to LC3B. Normally, LC3B causes misfolded proteins to become degraded, but in the case of Parkinson’s, LC3B becomes trapped in protein aggregates and becomes inactive.
A rare genetic mutation interferes with dopamine transporters in the brain, causing Parkinson’s-like symptoms in children.
A new study reveals a potential link between REM sleep behavior disorder and an increased risk of developing Parkinson’s disease. Researchers say the sleep disorder alters cerebral blood flow, leading to a lack of oxygen in brain tissue. This, in the l…
A new gel that contains levodopa can adhere to nasal tissue. The gel releases levodopa directly into the blood and brain. Researchers say the preliminary data reveals the gel has proven to be effective in animal models.
CRISPR gene-editing technology allowed researchers to pinpoint specific neurons and mechanisms related to the effects of oxidative stress in the brain.
Researchers have identified a layer of genetic material involved in controlling the production of tau in the brain. The material is part of a larger family of non-coding genes that regulate and control other brain proteins associated with neurodegenera…
Researchers identify five genetic loci linked to the progression of Parkinson’s disease.
A new study reports on an association between specific gut bacteria species and the manifestation of neurodegenerative disorders.
Using single nucleus RNA sequencing, researchers have mapped 21 subtypes of motor neurons in the spinal cords of mice.
Study finds evidence of inflammation in the blood of patients during the early stages of Parkinson’s disease. The findings support the theory that inflammation is a driver of the neurodegenerative disorder. The effect was most noticed in women with Par…
The VGLUT protein is more abundant in the dopamine neurons of female fruit flies, rodents, and humans than in males. The finding shed light on why females have greater resilience to age-related dopamine neuron loss and disorders such as Parkinson’s dis…
A new model of Parkinson’s disease sheds light on the asymmetrical motor symptoms, and other disorders, associated with this disease.